The much hyped Hotmail beta looks way too much like the default Zope/Plone interface. Other than on the odd weblog or two, I just cannot stand layouts comprising vast expanses of white, broken up by grey text and pastel colour borders. Even for someone like me, who has pretty okay eyesight, the interface is very confusing to use for the lack of clear demarcations.
Moreover, there is nothing great the beta has added to the product and if the Microsoftians think this is going to grab the e-mail market by its balls and give Gmail a run for its money, they don't understand the first thing about the balls they are dealing with. Psst.. it does not work on Firefox either. At least not yet.